Oral testosterone replacement therapy

Oral testosterone undecanoate is less effective than other testosterone formulations. It has low (under 10%) and variable bioavailability and a short duration of action, so multiple daily doses are required.

For oral testosterone replacement therapy, use:

testosterone undecanoate 120 to 160 mg orally, daily in 2 divided doses for 2 to 3 weeks. Adjust dose according to clinical response and serum testosterone concentration (usual range 80 mg to 240 mg daily). male androgen deficiency, oral therapy testosterone

See Monitoring testosterone replacement therapy for guidance on adjusting testosterone therapy.