Antimicrobial stewardship (AMS) in residential aged-care facilities

Older people, especially those living in residential aged-care facilities, have increased susceptibility to infection due to physiological changes that occur with aging. There are high rates of antimicrobial use in residential aged-care facilities. The rate of antimicrobial resistance is higher in residential aged-care facilities than in hospitals Australian Commission on Safety and Quality in Health Care (ACSQHC), 2021. Patients in residential aged-care facilities often move in and out of hospital, which increases the risk of infection. Antimicrobial use in residential aged-care facilities is often inappropriate; this is likely due to the difficulty in diagnosing infection in older adults, especially those with comorbiditiesAustralian Commission on Safety and Quality in Health Care (ACSQHC), 2018. A significant number of patients in residential aged-care facilities are prescribed antimicrobials for prolonged durations; these include prescriptions for prophylactic therapy despite there being limited supporting dataAustralian Commission on Safety and Quality in Health Care (ACSQHC), 2023.

The Aged Care Quality and Safety Commission require residential aged-care providers to:

Implementation of organisation-wide antimicrobial stewardship (AMS) activities promote safe and effective use of antimicrobials for residents. These activities complement good infection prevention and control strategies, and support the efforts of general practitioners who care for residents. The Australian Commission on Safety and Quality in Health Care (ACSQHC) recommends 5 essential strategies for effective AMS in residential aged-care facilities, see Five essential strategies for effective antimicrobial stewardship in residential aged-care facilities.
Table 1. Five essential strategies for effective antimicrobial stewardship in residential aged-care facilities

Australian Commission on Safety and Quality in Health Care (ACSQHC), 2021

Strategy

Actions to be considered

Provide access to and use evidence-based infection assessment tools and guidelines

Participation in online learning modules on antimicrobial stewardship (AMS)

Participation in audit and feedback activities for prescribing of antimicrobials (eg Aged Care National Antimicrobial Prescribing Survey)

Communication within the treating team about AMS priorities, results of evaluation and use of guidelines

Promotion of safe and effective use of antimicrobials that are evidence based

Staff education about antimicrobial resistance and AMS

Prescribe according to Therapeutic Guidelines: Antibiotic

Review antimicrobial prescribing

Use shared decision making with patients for antimicrobial decisions (if appropriate)

Provide information for residents and their families (see Antimicrobial stewardship (AMS) resources for patients)

Discuss vaccination to minimise need for antibiotics

Consider the indication for ‘when required’ antimicrobials

Review appropriateness of antimicrobial use for prophylaxis

Consider whether broad-spectrum antimicrobials or parental antimicrobials are indicated in end-stage illness

Unless there is confirmed bacterial infection, refrain from prescribing antimicrobials for upper respiratory tract infections (eg chronic obstructive pulmonary disease [COPD], bronchiectasis, acute bronchitis)

Refrain from prescribing antimicrobials for asymptomatic bacteriuria

Review the antimicrobial prescribed after 2 to 3 days of treatment to follow up clinical response, adverse effects and microbiology results. Change to directed rather than empirical prescribing

Improve documentation

Specify the start date of antimicrobial therapy on the prescription

Specify the duration of antimicrobial therapy on the prescription

Document the indication of antimicrobial therapy on the prescription

Use microbiological testing or diagnostic tests

Use targeted treatment for organisms from chronic wounds only if clinically infected

Consider the appropriateness of antimicrobial use based on clinical appearance (eg skin rash or irritation incorrectly identified as infection). See Assessing patients with an ulcer or wound

Understand the difference between urinalysis and urine culture. Urinalysis or collection of urine cultures should not occur from asymptomatic patients

Refrain from prescribing antimicrobials without microbiological investigation

Education regarding obtaining an appropriate sample (particularly in patients who are incontinent, uncooperative, or have a urinary catheter)

Implement infection prevention and control practices

Reduce the risk of patients acquiring a preventable infection

Support appropriate management of infections

Effective infection prevention strategies include wound management, optimal oral health and good toileting practices

Useful resources for antimicrobial stewardship in aged care include: