Antibiotic therapy for chronic bacterial prostatitis
Base the antibiotic choice for chronic bacterial prostatitis on the results of culture and susceptibility testing. If susceptibility is confirmed, suitable regimens include:
1ciprofloxacin 500 mg orally, 12-hourly for 4 weeks. For dosage adjustment in adults with kidney impairment, see ciprofloxacin oral dosage adjustment ciprofloxacin
OR
2trimethoprim 300 mg orally, daily for 4 weeks. For dosage adjustment in adults with kidney impairment, see trimethoprim dosage adjustment trimethoprim
OR
2trimethoprim+sulfamethoxazole 160+800 mg orally, 12-hourly for 4 weeks. For dosage adjustment in adults with kidney impairment, see trimethoprim+sulfamethoxazole dosage adjustment. trimethoprim + sulfamethoxazole
If recurrence occurs after 4 weeks of antibiotic therapy, seek urological advice. Do not repeat courses of antibiotic therapy unless a recognised uropathogen is found on culture from a symptomatic patient and it has been advised by a urologist.