Management of low- to moderate-severity HAP in patients with immune compromise

For patients with immune compromise who do not have profound immunosuppression, no change to standard empirical antibiotic therapy for low- to moderate-severity HAP is required.

For patients with immune compromise who have significant immunosuppression (eg recent solid organ or haematopoietic stem cell transplant) and low- to moderate-severity HAP, consider performing investigations for a broader range of pathogens. Seek expert advice on whether to adjust empirical antibiotic therapy while awaiting the results of investigations.