References: Hospital-acquired sepsis or septic shock of unknown source in adults
Abdul-Aziz MH, Hammond NE, Brett SJ, Cotta MO, De Waele JJ, Devaux A, et al. Prolonged vs Intermittent Infusions of beta-Lactam Antibiotics in Adults With Sepsis or Septic Shock: A Systematic Review and Meta-Analysis. JAMA 2024;332(8):638-48. https://pubmed.ncbi.nlm.nih.gov/38864162/
Burston J, Adhikari S, Hayen A, Doolan H, Kelly ML, Fu K, et al. A Role for Antimicrobial Stewardship in Clinical Sepsis Pathways: a Prospective Interventional Study. Infect Control Hosp Epidemiol 2017;38(9):1032-8. https://www.ncbi.nlm.nih.gov/pubmed/28693625
Dickinson JD, Kollef MH. Early and adequate antibiotic therapy in the treatment of severe sepsis and septic shock. Curr Infect Dis Rep 2011;13(5):399-405. https://www.ncbi.nlm.nih.gov/pubmed/21822574
Dulhunty JM, Brett SJ, De Waele JJ, Rajbhandari D, Billot L, Cotta MO, et al. Continuous vs Intermittent beta-Lactam Antibiotic Infusions in Critically Ill Patients With Sepsis: The BLING III Randomized Clinical Trial. JAMA 2024;332(8):629-37. https://pubmed.ncbi.nlm.nih.gov/38864155/