Mediastinitis related to perioral or parapharyngeal infection

For mediastinitis related to perioral or parapharyngeal infection, use the results of culture and susceptibility testing to guide initial therapy. If microbiology results are not available, the choice of empirical antibiotic therapy depends on whether the patient has sepsis or septic shock:

• for treatment regimens for patients without sepsis or septic shock, see here
• for treatment regimens for patients with sepsis or septic shock, see here.