Empirical therapy for nonsevere postprocedural pelvic infection
For empirical therapy in nonpregnant patients who do not have features of severe postprocedural pelvic infection, use:
amoxicillin+clavulanate 875+125 mg orally, 12-hourly for 14 days. For dosage adjustment in adults with kidney impairment, see amoxicillin+clavulanate oral dosage adjustment. amoxicillin + clavulanate amoxicillin+clavulanate amoxicillin+clavulanate
For patients with hypersensitivity to penicillins, use:
trimethoprim+sulfamethoxazole 160+800 mg orally, 12-hourly for 14 days. For dosage adjustment in adults with kidney impairment, see trimethoprim+sulfamethoxazole dosage adjustment trimethoprim + sulfamethoxazole trimethoprim+sulfamethoxazole trimethoprim+sulfamethoxazole
PLUS
metronidazole 400 mg orally, 12-hourly for 14 days. metronidazole metronidazole metronidazole
Assess the response to therapy within 72 hours and if the patient has not improved, review the diagnosis and consider switching to intravenous therapy – see Empirical therapy for severe postprocedural pelvic infection.