Practical information on using fusidate sodium

Fusidate sodium (fusidic acid, sodium fusidate) is a narrow-spectrum antibiotic, mainly active against Staphylococcus aureus.

Fusidate sodium should always be used in combination with other antibiotics because resistance develops readily. It should not be used topically.

Fusidate sodium has many clinically significant drug interactions (eg a potentially fatal interaction with statinsMedicines and Healthcare products Regulatory Agency (MHRA), 2014). Consult an appropriate resource on drug interactions if starting or stopping fusidate sodium in patients taking other drugs.