Additional therapy for patients with spontaneous bacterial peritonitis at high risk of developing hepatorenal syndrome
Patients with spontaneous bacterial peritonitis and chronic liver disease who have kidney impairment or jaundice are at high risk of developing hepatorenal syndrome. Treatment with albumin reduces the rate of acute kidney injury and improves survival in these patients.
For adults with spontaneous bacterial peritonitis and chronic liver disease who have kidney impairment or jaundice, use:
albumin 20%, 1.5 g/kg (7.5 mL/kg) intravenously, within 6 hours of diagnosis and 1 g/kg (5 mL/kg) intravenously, as a single dose on day 3.
For children, seek expert advice about the use of albumin.
For other strategies that may prevent kidney impairment in patients at high risk of developing hepatorenal syndrome, see Hepatorenal syndrome.
