Postcoital antibiotic prophylaxis for recurrent UTI in nonpregnant females
Do not give antibiotic prophylaxis to patients with asymptomatic bacteriuria.
For nonpregnant females1 in whom episodes of recurrent urinary tract infection (UTI) are triggered by sexual intercourse, intermittent postcoital prophylaxis may be appropriate; use:Barber, 2013Bonkat, 2024Dason, 2011Zare, 2022
1nitrofurantoin 50 mg orally as a single dose, taken within 2 hours after sexual intercourse; maximum of one dose daily. For dosage adjustment in adults with kidney impairment, see nitrofurantoin dosage adjustment nitrofurantoin nitrofurantoin nitrofurantoin
OR
2trimethoprim 150 mg orally as a single dose, taken within 2 hours after sexual intercourse; maximum of one dose daily. For dosage adjustment in adults with kidney impairment, see trimethoprim dosage adjustment trimethoprim trimethoprim trimethoprim
OR
3cefalexin 250 mg orally as a single dose, taken within 2 hours after sexual intercourse; maximum of one dose daily. For dosage adjustment in adults with kidney impairment, see cefalexin dosage adjustment. cefalexin cefalexin cefalexin