Dosage of danaparoid

Danaparoid is a parenteral low molecular weight heparinoid consisting of heparin sulfate, dermatan sulfate and chondroitin sulfate. It has primarily anti-Xa activity. Danaparoid is predominantly excreted via the kidneys so it should be avoided in patients with a calculated creatinine clearance (CrCl) less than 30 mL/min; seek specialist advice.

The route of administration and the dosage of danaparoid vary according to the indication. For example:

• heparin-induced thrombocytopenia (HIT)
• uncommonly for venous thromboembolism (VTE) prophylaxis in surgical patients; see the danaparoid product information for dosage.