Prevalence of conditions associated with fatigue

Disease prevalence data are helpful when assessing the pretest probability of disease. A guide to the estimated prevalence in the general population of conditions associated with fatigue is given in A guide to the prevalence of conditions associated with fatigue in children and adolescents for children and adolescents, and A guide to the prevalence of conditions associated with fatigue in adults for adults.
Table 1. A guide to the prevalence of conditions associated with fatigue in children and adolescents

[NB1]

Condition associated with fatigue

Prevalence in general population [NB2]

Children

Adolescents

anaemia

[NB3][NB4] [NB5][NB6]

8% of preschool children are anaemic, with iron deficiency as a major cause; likely higher in disadvantaged children

2% in 15- to 24-year age group are anaemic

iron deficiency most common cause; prevalence of iron-deficiency anaemia higher in females than males

prevalence of iron-deficiency anaemia in adolescents who are pregnant is around 14%; may be significantly higher (up to 50%) in Aboriginal adolescents who are pregnant, particularly those in remote communities

obesity

[NB7]

7 to 9% in 2- to 14-year age group

9% in 15- to 17-year age group

depression

[NB5]

1% in 0- to 14-year age group

12% in 15- to 24-year age group

obstructive sleep apnoea

[NB8][NB9]

1 to 5%

1 to 5%

diabetes (all types)

[NB5]

0.2% in 0- to 14-year age group

0.6% in 15- to 24-year age group

illicit drug use

[NB10]

no data

10% in 14- to 17-year age group have recently used an illicit drug

excessive alcohol intake

[NB11]

no data

9% of 14- to 17-year age group exceed the Australian alcohol consumption guidelines for adult single-occasion risk

malignancy

[NB5]

0.1% in 0- to 14-year age group

0.1% in 15- to 24-year age group

Note:

NB1: The following data indicate the prevalence of conditions in the general population, not the prevalence of conditions in patients presenting with fatigue.

NB2: Prevalence data are difficult to determine and the figures in this table should be used only as a guide. Figures may be significantly higher in certain population groups. Some figures have been rounded for ease of reading. Age brackets reflect available data sources.

NB3: Royal Children’s Hospital Melbourne (RCH). Anaemia [clinical guideline]. Melbourne: RCH; Last updated January 2019. URL

NB4: Mitchinson C, Strobel N, McAullay D, McAuley K, Bailie R, Edmond KM. Anemia in disadvantaged children aged under five years; quality of care in primary practice. BMC Pediatr 2019;19(1):178. URL

NB5: Australian Bureau of Statistics (ABS). National Health Survey: First results 2017-18 financial year. Canberra: Australian Government; 2018. URL

NB6: Department of Health [Australia]. 30 Anaemia. In: Pregnancy Care Guidelines. Canberra: Australian Government; Last updated 17 May 2019. URL

NB7: Australian Institute of Health and Welfare (AIHW). Data tables: Overweight and obesity: an interactive insight, 2020. Canberra: Australian Government; 2020. URL

NB8: Nixon GM, Davey M. Sleep apnoea in the child. Aust Fam Physician 2015;44(6):352-5. URL

NB9: Marcus CL, Brooks LJ, Draper KA, Gozal D, Halbower AC, Jones J, et al. Diagnosis and management of childhood obstructive sleep apnea syndrome. Pediatrics 2012;130(3):576-84. URL

NB10: Australian Institute of Health and Welfare (AIHW). Alcohol, tobacco & other drugs in Australia: Younger people. Canberra: AIHW; 2021. URL

NB11: Australian Institute of Health and Welfare (AIHW). Alcohol, tobacco & other drugs in Australia: Younger people. Canberra: AIHW; 2021. URL

Table 2. A guide to the prevalence of conditions associated with fatigue in adults

[NB1]

Condition associated with fatigue

Prevalence in general population [NB2]

Young to middle-aged females

Young to middle-aged males

Older people

obesity

[NB3]

14 to 35% of females aged 18 to 54 years

18 to 41% of males aged 18 to 54 years

20 to 40% of people aged 55 to 84 years

20% in people aged 85 and older

anxiety

[NB4]

16 to 20% of females aged 25 to 54 years

10 to 13% of males aged 25 to 54 years

9 to 14% of people aged 55 years and older

anaemia

[NB5][NB6][NB7]

15% have anaemia, with iron deficiency as a major cause

2 to 5% iron-deficiency anaemia

risk of anaemia increases with age (16% at age 75)

maternal postnatal depression

[NB8]

16%

not applicable

not applicable

excessive alcohol intake

[NB9]

9% of females exceed the Australian alcohol consumption guidelines for lifetime risk

24% of males exceed the Australian alcohol consumption guidelines for lifetime risk

10% of females and 29% of males aged 55 to 64 years; 9% of females and 27% of males aged 65 to 74 years; 6% of females and 17% of males aged 75 years and older exceed the Australian alcohol consumption guidelines for lifetime risk

depression

[NB4]

12 to 17% of females aged 25 to 54 years

10 to 13% of males aged 25 to 54 years

15% of people aged 55 to 64 years

7 to 13% of people aged 65 years and older

thyroid dysfunction

[NB4]

5 to 8% of females aged 25 to 54 years

0.6 to 0.9% of males aged 25 to 54 years

13 to 15% of females and 2 to 6% of males aged 55 years and older

illicit drug use

[NB10]

10 to 25% of females have recently used

16 to 36% of males have recently used

7% of people aged 60 and older have recently used

diabetes (all types)

[NB4]

0.3 to 4% of females aged 25 to 54 years

2 to 5% of males aged 25 to 54 years

10% of people aged 55 to 64 years

17% of people aged 65 years and older

obstructive sleep apnoea

[NB11]

9 to 38% (higher in males and older people) when defined as disordered breathing identified by a sleep study (apnoea–hypopnoea index of 5 or more events per hour)

as high as 90% in men and 78% in women in advanced age groups (60 to 85 years)

heart failure

[NB4]

up to 0.1% of females aged 25 to 54 years

up to 0.4% of males aged 25 to 54 years

1 to 4% of people aged 55 years and older

malignancy

[NB4]

0.1 to 1.3% of females aged 25 to 54 years

0.2 to 1.5% of males aged 25 to 54 years

4 to 9% in people aged 55 and older; increases with age

coeliac disease

[NB12]

affects approximately 1 in 70 Australians; can develop at any age and affects both men and women

chronic kidney disease

[NB4]

less than 1% of females aged up to 54 years

1.1% of males aged 45 to 54 years; less than 1% prior to this

1 to 7% of people aged 55 years and older; increases with age

Parkinson disease

[NB13]

0.1 to 0.2%, increasing to 1% of people over the age of 60; slightly more common in males than in females

haemochromatosis

[NB14]

0.5% of Australians of Northern European descent are at risk; often becomes apparent after age 40 (can be later in females)

Note:

NB1: The following data indicate the prevalence of conditions in the general population, not the prevalence of conditions in patients presenting with fatigue.

NB2: Prevalence data are difficult to determine and the figures in this table should be used only as a guide. Figures may be significantly higher in certain population groups. Some figures have been rounded for ease of reading. Age brackets reflect available data sources. Where age- or gender-specific data are not available, general data have been included for guidance.

NB3: Australian Institute of Health and Welfare (AIHW). Data tables: Overweight and obesity: an interactive insight, 2020. Canberra: Australian Government; 2020. URL

NB4: Australian Bureau of Statistics (ABS). National Health Survey: First results 2017-18 financial year. Canberra: Australian Government; 2018. URL

NB5: Pasricha SR, Flecknoe-Brown SC, Allen KJ, Gibson PR, McMahon LP, Olynyk JK, et al. Diagnosis and management of iron deficiency anaemia: a clinical update. Med J Aust 2010;193(9):525-32. URL

NB6: Snook J, Bhala N, Beales ILP, Cannings D, Kightley C, Logan RP, et al. British Society of Gastroenterology guidelines for the management of iron deficiency anaemia in adults. Gut 2021;70(11):2030-51. URL

NB7: Australian Bureau of Statistics (ABS). Australian Health Survey: Biomedical Results for Chronic Diseases [2011-12 financial year]. Canberra: ABS; 2013. URL

NB8: Women’s Health Committee--Royal Australian and New Zealand College of Obstetricians and Gynaecologists (RANZCOG). Mental Health Care in the Perinatal Period [C-Obs 48]. Melbourne: RANZCOG; 2018. URL

NB9: Australian Bureau of Statistics (ABS). Alcohol consumption [2017-18 financial year]. Canberra: ABS; 2018. URL

NB10: Australian Institute of Health and Welfare (AIHW). Alcohol, tobacco & other drugs in Australia [2019 data]. Canberra: AIHW; 2021. URL

NB11: Senaratna CV, Perret JL, Lodge CJ, Lowe AJ, Campbell BE, Matheson MC, et al. Prevalence of obstructive sleep apnea in the general population: A systematic review. Sleep Med Rev 2017;34:70-81. URL

NB12: Coeliac Australia. Coeliac disease: What is coeliac disease? [internet]. Sydney: Coeliac Australia; Accessed Sept 2021. URL

NB13: Brain Foundation. Parkinson’s disease: Description [internet]. Sydney: Brain Foundation; Accessed Sept 2021. URL

NB14: Centre for Genetics Education. Fact Sheet 47-Hereditary haemochromatosis. Sydney: New South Wales Government; 2015. URL