Cytotoxic drug-induced nausea and vomiting in adults

eviQ, 2006.

Nausea and vomiting are common after chemotherapy, and oncology centres usually have their own guidelines for managing this complication. Cytotoxic drugs cause nausea and vomiting by peripheral stimulation of 5-HT₃–receptors (via vagal sensory afferent nerves), and possibly central stimulation of the chemoreceptor trigger zone.

Cytotoxic drugs vary in their potential to cause nausea and vomiting. The eviQ website contains detailed guidance on chemotherapy-induced nausea and vomiting.