Key references: Nausea and vomiting during pregnancy
Dormuth CR, Winquist B, Fisher A, Wu F, Reynier P, Suissa S, et al. Comparison of Pregnancy Outcomes of Patients Treated With Ondansetron vs Alternative Antiemetic Medications in a Multinational, Population-Based Cohort. JAMA Netw Open 2021;4(4):e215329. https://www.ncbi.nlm.nih.gov/pubmed/33890993
Huybrechts KF, Hernandez-Diaz S, Straub L, Gray KJ, Zhu Y, Patorno E, et al. Association of Maternal First-Trimester Ondansetron Use With Cardiac Malformations and Oral Clefts in Offspring. JAMA 2018;320(23):2429-37. https://www.ncbi.nlm.nih.gov/pubmed/30561479
Lavecchia M, Chari R, Campbell S, Ross S. Ondansetron in Pregnancy and the Risk of Congenital Malformations: A Systematic Review. J Obstet Gynaecol Can 2018;40(7):910-8. https://www.ncbi.nlm.nih.gov/pubmed/29754832
Lowe SA, Bowyer L, Beech A, Robinson H, Armstrong G, Marnoch C, et al. Guideline for the management of nausea and vomiting in pregnancy and hyperemesis gravidarum. Sydney: Society of Obstetric Medicine of Australia and New Zealand; 2019. https://www.somanz.org/approval-of-written-guidelines-by-somanz/
Zambelli-Weiner A, Via C, Yuen M, Weiner DJ, Kirby RS. First trimester ondansetron exposure and risk of structural birth defects. Reprod Toxicol 2019;83:14-20. https://www.ncbi.nlm.nih.gov/pubmed/30385129