Key references: Intrahepatic cholestasis of pregnancy

  • Chappell LC, Bell JL, Smith A, Linsell L, Juszczak E, Dixon PH, et al. Ursodeoxycholic acid versus placebo in women with intrahepatic cholestasis of pregnancy (PITCHES): a randomised controlled trial. Lancet 2019;394(10201):849–60. https://www.ncbi.nlm.nih.gov/pubmed/31378395
  • Geenes V, Chambers J, Khurana R, Shemer EW, Sia W, Mandair D, et al. Rifampicin in the treatment of severe intrahepatic cholestasis of pregnancy. Eur J Obstet Gynecol Reprod Biol 2015;189:59–63. https://www.ncbi.nlm.nih.gov/pubmed/25864112
  • LiverTox: clinical and research information on drug-induced liver injury [Internet]. Bethesda (MD): National Institute of Diabetes and Digestive and Kidney Diseases; 2012. https://www.ncbi.nlm.nih.gov/books/NBK547852/
  • Marathe JA, Lim WH, Metz MP, Scheil W, Dekker GA, Hague WM. A retrospective cohort review of intrahepatic cholestasis of pregnancy in a South Australian population. Eur J Obstet Gynecol Reprod Biol 2017;218:33–8. https://www.ncbi.nlm.nih.gov/pubmed/28926728
  • Monash Women’s Maternity Guideline Development Group. Cholestasis of pregnancy: Clinical guideline. Monash Health; 2019. https://monashhealth.org/health-professionals/maternity/guidelines-procedures/
  • Ovadia C, Seed PT, Sklavounos A, Geenes V, Di Ilio C, Chambers J, et al. Association of adverse perinatal outcomes of intrahepatic cholestasis of pregnancy with biochemical markers: results of aggregate and individual patient data meta-analyses. Lancet 2019;393(10174):899–909. https://www.ncbi.nlm.nih.gov/pubmed/30773280