References: Coagulopathy in patients with cirrhosis
European Association for the Study of the Liver. EASL Clinical Practice Guidelines on prevention and management of bleeding and thrombosis in patients with cirrhosis. J Hepatol 2022;76(5):1151-84. https://www.ncbi.nlm.nih.gov/pubmed/35300861
Intagliata NM, Argo CK, Stine JG, Lisman T, Caldwell SH, Violi F, et al. Concepts and controversies in haemostasis and thrombosis associated with liver disease: proceedings of the 7th International Coagulation in Liver Disease Conference. Thromb Haemost 2018;118(8):1491–506. https://www.ncbi.nlm.nih.gov/pubmed/30060258
Kubitza D, Roth A, Becka M, Alatrach A, Halabi A, Hinrichsen H, et al. Effect of hepatic impairment on the pharmacokinetics and pharmacodynamics of a single dose of rivaroxaban, an oral, direct Factor Xa inhibitor. Br J Clin Pharmacol 2013;76(1):89–98. https://www.ncbi.nlm.nih.gov/pubmed/23294275
Northup PG, Garcia-Pagan JC, Garcia-Tsao G, Intagliata NM, Superina RA, Roberts LN, et al. Vascular Liver Disorders, Portal Vein Thrombosis, and Procedural Bleeding in Patients With Liver Disease: 2020 Practice Guidance by the American Association for the Study of Liver Diseases. Hepatology 2021;73(1):366-413. https://www.ncbi.nlm.nih.gov/pubmed/33219529
O’Leary JG, Greenberg CS, Patton HM, Caldwell SH. AGA clinical practice update: coagulation in Cirrhosis. Gastroenterology 2019;157(1):34-43 e1. https://www.ncbi.nlm.nih.gov/pubmed/30986390
Patel IJ, Rahim S, Davidson JC, Hanks SE, Tam AL, Walker TG, et al. Society of Interventional Radiology consensus guidelines for the Periprocedural management of thrombotic and bleeding risk in patients undergoing percutaneous image-guided interventions-part II: recommendations. J Vasc Interv Radiol 2019;30(8):1168-84 e1. https://www.ncbi.nlm.nih.gov/pubmed/31229333
Peck-Radosavljevic M, Simon K, Iacobellis A, Hassanein T, Kayali Z, Tran A, et al. Lusutrombopag for the treatment of thrombocytopenia in patients with chronic liver disease undergoing invasive procedures (L-PLUS 2). Hepatology 2019;70(4):1336–48. https://www.ncbi.nlm.nih.gov/pubmed/30762895
Qamar A, Vaduganathan M, Greenberger NJ, Giugliano RP. Oral anticoagulation in patients with liver disease. J Am Coll Cardiol 2018;71(19):2162–75. https://www.ncbi.nlm.nih.gov/pubmed/29747837
Terrault N, Chen YC, Izumi N, Kayali Z, Mitrut P, Tak WY, et al. Avatrombopag before procedures reduces need for platelet transfusion in patients with chronic liver disease and thrombocytopenia. Gastroenterology 2018;155(3):705–18. https://www.ncbi.nlm.nih.gov/pubmed/29778606