Tension-type headache
For infrequent tension-type headache, nonopioid analgesics are appropriate. A lower dose of aspirin than used for migraine can be effective. Use:
1 aspirin soluble 600 to 900 mg orally. Wait 4 to 6 hours before repeating dose if needed (maximum dose 2 g in 24 hours) headache, tension aspirin
OR
1 diclofenac potassium 50 mg orally. Wait 4 to 6 hours before repeating dose if needed (maximum dose 150 mg in 24 hours)1 headache, tension
OR
1 ibuprofen 400 mg orally. Wait 4 to 6 hours before repeating dose if needed (maximum dose 2.4 g in 24 hours) headache, tension ibuprofen
OR
1 naproxen 500 to 750 mg orally. Wait 4 to 6 hours before repeating dose if needed (maximum dose 1250 mg in 24 hours) headache, tension naproxen
OR
1 paracetamol soluble 1 g orally. Wait 4 to 6 hours before repeating dose if needed (maximum dose 4 g in 24 hours). headache, tension paracetamol
The efficacy of nonopioid analgesics may decline with increasing headache frequency—if so, try adding a preventive drug (eg a tricyclic antidepressant). For more frequent tension-type headache, use:
1 amitriptyline 10 mg orally, once daily at night. Increase dose by 10 mg every 7 days to a maximum of 75 mg once daily at night, for 8 weeks, then review headache, tension, prophylaxis amitriptyline
OR
1 nortriptyline 10 mg orally, once daily at night. Increase dose by 10 mg every 7 days to a maximum of 75 mg once daily at night, for 8 weeks, then review. headache, tension, prophylaxis nortriptyline
If these drugs are effective, continue therapy for 6 months and then consider a trial of withdrawing therapy.
If no response to a preventive drug after 8 to 12 weeks, switch to another preventive drug or refer for expert advice. As an alternative preventive drug, use:
1 mirtazapine 15 to 30 mg orally, once daily at night, for 8 to 12 weeks, then review headache, tension, prophylaxis mirtazapine
OR
1 venlafaxine modified-release 75 mg orally, in the morning after food. Increase dose according to tolerability and patient response to 150 mg daily. Review after 8 to 12 weeks. headache, tension, prophylaxis venlafaxine
