Key references: Restless legs syndrome and periodic limb movements of sleep/wakefulness

  • Aurora RN, Kristo DA, Bista SR, Rowley JA, Zak RS, Casey KR, et al. Update to the AASM Clinical Practice Guideline: “The treatment of restless legs syndrome and periodic limb movement disorder in adults-an update for 2012: practice parameters with an evidence-based systematic review and meta-analyses”. Sleep 2012;35(8):1037. https://www.ncbi.nlm.nih.gov/pubmed/22851800
  • Aurora RN, Kristo DA, Bista SR, Rowley JA, Zak RS, Casey KR, et al. The treatment of restless legs syndrome and periodic limb movement disorder in adults--an update for 2012: practice parameters with an evidence-based systematic review and meta-analyses: an American Academy of Sleep Medicine Clinical Practice Guideline. Sleep 2012;35(8):1039–62. https://www.ncbi.nlm.nih.gov/pubmed/22851801
  • Garcia-Borreguero D, Cano-Pumarega I. New concepts in the management of restless legs syndrome. BMJ 2017;356:j104. https://www.ncbi.nlm.nih.gov/pubmed/28242627
  • Garcia-Borreguero D, Kohnen R, Silber MH, Winkelman JW, Earley CJ, Hogl B, et al. The long-term treatment of restless legs syndrome/Willis-Ekbom disease: evidence-based guidelines and clinical consensus best practice guidance: a report from the International Restless Legs Syndrome Study Group. Sleep Med 2013;14(7):675–84. https://www.ncbi.nlm.nih.gov/pubmed/23859128
  • Garcia-Borreguero D, Silber MH, Winkelman JW, Hogl B, Bainbridge J, Buchfuhrer M, et al. Guidelines for the first-line treatment of restless legs syndrome/Willis-Ekbom disease, prevention and treatment of dopaminergic augmentation: a combined task force of the IRLSSG, EURLSSG, and the RLS-foundation. Sleep Med 2016;21:1–11. https://www.ncbi.nlm.nih.gov/pubmed/27448465
  • Garcia-Borreguero D, Stillman P, Benes H, Buschmann H, Chaudhuri KR, Rodriguez VM, et al. Algorithms for the diagnosis and treatment of restless legs syndrome in primary care. BMC Neurol 2011;11:28. https://www.ncbi.nlm.nih.gov/pubmed/21352569
  • Hornyak M, Scholz H, Kohnen R, Bengel J, Kassubek J, Trenkwalder C. What treatment works best for restless legs syndrome? Meta-analyses of dopaminergic and non-dopaminergic medications. Sleep Med Rev 2014;18(2):153–64. https://www.ncbi.nlm.nih.gov/pubmed/23746768
  • Scholz H, Trenkwalder C, Kohnen R, Riemann D, Kriston L, Hornyak M. Dopamine agonists for restless legs syndrome. Cochrane Database Syst Rev 2011;(3):CD006009. https://www.ncbi.nlm.nih.gov/pubmed/21412893
  • Scholz H, Trenkwalder C, Kohnen R, Riemann D, Kriston L, Hornyak M. Levodopa for restless legs syndrome. Cochrane Database Syst Rev 2011;(2):CD005504. https://www.ncbi.nlm.nih.gov/pubmed/21328278
  • Wijemanne S, Jankovic J. Restless legs syndrome: clinical presentation diagnosis and treatment. Sleep Med 2015;16(6):678–90. https://www.ncbi.nlm.nih.gov/pubmed/25979181
  • Wilt TJ, MacDonald R, Ouellette J, Khawaja IS, Rutks I, Butler M, et al. Pharmacologic therapy for primary restless legs syndrome: a systematic review and meta-analysis. JAMA Intern Med 2013;173(7):496–505. https://www.ncbi.nlm.nih.gov/pubmed/23460396
  • Winkelman JW, Armstrong MJ, Allen RP, Chaudhuri KR, Ondo W, Trenkwalder C, et al. Practice guideline summary: Treatment of restless legs syndrome in adults: Report of the Guideline Development, Dissemination, and Implementation Subcommittee of the American Academy of Neurology. Neurology 2016;87(24):2585–93. https://www.ncbi.nlm.nih.gov/pubmed/27856776
  • Yeh P, Walters AS, Tsuang JW. Restless legs syndrome: a comprehensive overview on its epidemiology, risk factors, and treatment. Sleep Breath 2012;16(4):987–1007. https://www.ncbi.nlm.nih.gov/pubmed/22038683