Key references: The role of opioids for chronic noncancer pain

  • Busse JW, Wang L, Kamaleldin M, Craigie S, Riva JJ, Montoya L, et al. Opioids for chronic noncancer pain: A systematic review and meta-analysis. JAMA 2018;320(23):2448–60.https://www.ncbi.nlm.nih.gov/pubmed/30561481
  • Frank JW, Lovejoy TI, Becker WC, Morasco BJ, Koenig CJ, Hoffecker L, et al. Patient Outcomes in dose reduction or discontinuation of long-term opioid therapy: a systematic review. Ann Intern Med 2017;167(3):181–91.https://www.ncbi.nlm.nih.gov/pubmed/28715848
  • Kim S, Slaven JE, Ang DC. Sustained benefits of exercise-based motivational interviewing, but only among nonusers of opioids in patients with fibromyalgia. J Rheumatol 2017;44(4):505–11.https://www.ncbi.nlm.nih.gov/pubmed/27909084
  • Krebs EE, Gravely A, Nugent S, Jensen AC, DeRonne B, Goldsmith ES, et al. Effect of opioid vs nonopioid medications on pain-related function in patients with chronic back pain or hip or knee osteoarthritis pain: The SPACE randomized clinical trial. JAMA 2018;319(9):872–82.https://www.ncbi.nlm.nih.gov/pubmed/29509867
  • McPherson S, Lederhos Smith C, Dobscha SK, Morasco BJ, Demidenko MI, Meath THA, et al. Changes in pain intensity after discontinuation of long-term opioid therapy for chronic noncancer pain. Pain 2018;159(10):2097–104. https://www.ncbi.nlm.nih.gov/pubmed/29905648
  • Pecina M, Karp JF, Mathew S, Todtenkopf MS, Ehrich EW, Zubieta JK. Endogenous opioid system dysregulation in depression: implications for new therapeutic approaches. Mol Psychiatry 2019;24(4):576–87.https://www.ncbi.nlm.nih.gov/pubmed/29955162