Rationalising thyroid replacement therapy in palliative care

Follow the principles of medication rationalisation when rationalising thyroid replacement therapy in palliative care.

Thyroid replacement therapy can usually be stopped in the last weeks of life. Patients are unlikely to become symptomatic for 2 to 4 weeks after stopping thyroid replacement therapy, and development of myxoedema coma is unlikely before 4 to 6 weeks.