Orthostatic hypotension caused by antipsychotics
For advice on monitoring for and preventing antipsychotic adverse effects, see Overview of antipsychotic adverse effects.
Many antipsychotics cause orthostatic hypotension—see Approximate relative frequency of common adverse effects of antipsychotics for approximate relative frequencies. Orthostatic hypotension usually subsides within a few days of starting treatment or a dose increase, or starting or stopping an interacting drug.
If orthostatic hypotension is severe and persistent, review and rationalise potentially contributing drugs (eg antihypertensives), reduce the antipsychotic dose if possible, or switch to an antipsychotic with less effect on blood pressure.