Antipsychotics for agitation in adults and young people with acute mania

If an antipsychotic is preferred (see Principles of treatment for agitation in adults and young people with acute mania), use a suitable dose of the patient’s antipsychotic as required, but do not exceed the maximum daily dose of the antipsychotic (including regular doses). After the agitation has resolved, do not continue the antipsychotic at the increased dose to manage mania.

If the patient remains acutely agitated and at risk of harming themselves or others 30 to 60 minutes after the administration of the antipsychotic, see Pharmacological management for acute behavioural disturbance in adults or Pharmacological management for acute behavioural disturbance in older people for further advice.