Preventing delirium in adults

If an adult is at risk of delirium, regularly monitor them for signs of delirium (ie changes in behaviour, cognition and physical condition) and instigate a multicomponent preventive strategy, personalised to their needs and setting. As appropriate, this strategy should include:

  • treating medical conditions—see Risk factors for delirium in adults
  • reviewing drugs for their potential benefit versus risk of harm—avoid using drugs that commonly cause or contribute to delirium and polypharmacy
  • assessing pain and providing pain relief
  • promoting healthy urinary and bowel function
  • supporting and encouraging safe mobilisation, especially to the toilet
  • providing adequate hydration and nutrition and, if needed, assistance with eating and drinking
  • encouraging use of and ensuring access to glasses and hearing aids
  • avoiding medical lines and tubes (eg catheters, drains), unless necessary; if used, remove them as soon as possible
  • promoting good sleep practices
  • providing lighting that approximates the time of day
  • closely involving family, carers or significant others who can support the patient
  • avoiding physical and chemical restraints
  • using visual and auditory cues (eg providing an orientation board, a clock and a calendar) to orientate
  • providing a quiet environment (eg a private room)
  • avoiding movement between beds and wards
  • encouraging cognition-stimulating activities (eg talking, reminiscing).

At the time of writing, there is insufficient evidence of benefit to recommend any drug (eg antipsychotics, melatonin, acetylcholinesterase inhibitors) to prevent delirium1.

1 Dexmedetomidine is sometimes used to prevent delirium in patients in intensive care settings—it has reduced the incidence of delirium in some studies but, evidence is conflicting and it can increase the incidence of adverse effects.Return