Assessing relapse in psychoses including schizophrenia in adults and young people

If an apparent relapse occurs, assess the patient to determine the cause(s). Consider potential contributors to relapse. Exclude other diagnoses (see examples in Possible diagnoses in a patient experiencing positive psychotic signs or symptoms); assess for delirium because it is an often overlooked cause of apparent relapse. Consider whether the patient was comprehensively assessed at the time of the first episode of psychosis or a previous relapse, and whether additional investigations should be undertaken (eg tests for autoimmune psychosis)—see Assessments to help identify cause(s) of psychotic signs and symptoms.