Adverse effects

Some adverse effects associated with noninvasive ventilation are:

  • skin breakdown at mask contact point (especially at the nasal bridge when using oro-nasal masks)—this should not occur with appropriate mask fitting. Do not overtighten mask. A prophylactic hydrocolloid dressing may be used
  • rhinorrhoea—may be reduced by the use of ipratropium nasal spray and by incorporating a heated humidifier in the circuit1
  • retention of secretions—may be overcome by humidification of air, bronchodilators and regular chest physiotherapy
  • gastric distension—may cause discomfort. Consider lowering both IPAP and EPAP.
1 Ipratropium nasal spray formulations were discontinued in Australia in December 2021.Return