Key references: Obstructive sleep apnoea in children

Causes of obstructive sleep apnoea in children

  • Dyken ME, Lin-Dyken DC, Poulton S, Zimmerman MB, Sedars E. Prospective polysomnographic analysis of obstructive sleep apnea in down syndrome. Arch Pediatr Adolesc Med 2003;157(7):655–60. https://www.ncbi.nlm.nih.gov/pubmed/12860786
  • Marcus CL, Brooks LJ, Draper KA, Gozal D, Halbower AC, Jones J, et al. Diagnosis and management of childhood obstructive sleep apnea syndrome. Pediatrics 2012;130(3):576–84. https://www.ncbi.nlm.nih.gov/pubmed/22926173
  • Maris M, Verhulst S, Wojciechowski M, Van de Heyning P, Boudewyns A. Prevalence of obstructive sleep apnea in children with down syndrome. Sleep 2016;39(3):699–704. https://www.ncbi.nlm.nih.gov/pubmed/26612391
  • Nixon GM, Kermack AS, Davis GM, Manoukian JJ, Brown KA, Brouillette RT. Planning adenotonsillectomy in children with obstructive sleep apnea: the role of overnight oximetry. Pediatrics 2004;113(1 Pt 1):e19–25. https://www.ncbi.nlm.nih.gov/pubmed/14702490
  • Shott SR, Amin R, Chini B, Heubi C, Hotze S, Akers R. Obstructive sleep apnea: should all children with Down syndrome be tested? Arch Otolaryngol Head Neck Surg 2006;132(4):432–6. https://www.ncbi.nlm.nih.gov/pubmed/16618913
  • Simpson R, Oyekan AA, Ehsan Z, Ingram DG. Obstructive sleep apnea in patients with Down syndrome: current perspectives. Nat Sci Sleep 2018;10:287–93. https://www.ncbi.nlm.nih.gov/pubmed/30254502
  • Trois MS, Capone GT, Lutz JA, Melendres MC, Schwartz AR, Collop NA, et al. Obstructive sleep apnea in adults with Down syndrome. J Clin Sleep Med 2009;5(4):317–23. https://www.ncbi.nlm.nih.gov/pubmed/19968008

Clinical assessment of obstructive sleep apnoea in children

  • Piteo AM, Lushington K, Roberts RM, van den Heuvel CJ, Nettelbeck T, Kohler MJ, et al. Prevalence of snoring and associated factors in infancy. Sleep Med 2011;12(8):787–92. https://www.ncbi.nlm.nih.gov/pubmed/21865083
  • Raynes-Greenow CH, Hadfield RM, Cistulli PA, Bowen J, Allen H, Roberts CL. Sleep apnea in early childhood associated with preterm birth but not small for gestational age: a population-based record linkage study. Sleep 2012;35(11):1475–80. https://www.ncbi.nlm.nih.gov/pubmed/23115396
  • Soh HJ, Rowe K, Davey MJ, Horne RSC, Nixon GM. The OSA-5: Development and validation of a brief questionnaire screening tool for obstructive sleep apnea in children. Int J Pediatr Otorhinolaryngol 2018;113:62–6. https://www.ncbi.nlm.nih.gov/pubmed/30174012

Treatment of obstructive sleep apnoea in children

  • Bluher AE, Brawley CC, Cunningham TD, Baldassari CM. Impact of montelukast and fluticasone on quality of life in mild pediatric sleep apnea. Int J Pediatr Otorhinolaryngol 2019;125:66–70. https://www.ncbi.nlm.nih.gov/pubmed/31260810
  • Brouillette RT, Manoukian JJ, Ducharme FM, Oudjhane K, Earle LG, Ladan S, et al. Efficacy of fluticasone nasal spray for pediatric obstructive sleep apnea. J Pediatr 2001;138(6):838–44. https://www.ncbi.nlm.nih.gov/pubmed/11391326
  • Chan CC, Au CT, Lam HS, Lee DL, Wing YK, Li AM. Intranasal corticosteroids for mild childhood obstructive sleep apnea--a randomized, placebo-controlled study. Sleep Med 2015;16(3):358–63. https://www.ncbi.nlm.nih.gov/pubmed/25650159
  • Kheirandish-Gozal L, Bandla HP, Gozal D. Montelukast for children with obstructive sleep apnea: results of a double-blind, randomized, placebo-controlled trial. Ann Am Thorac Soc 2016;13(10):1736–41. https://www.ncbi.nlm.nih.gov/pubmed/27439031
  • Liming BJ, Ryan M, Mack D, Ahmad I, Camacho M. Montelukast and nasal corticosteroids to treat pediatric obstructive sleep apnea: a systematic review and meta-analysis. Otolaryngol Head Neck Surg 2019;160(4):594–602. https://www.ncbi.nlm.nih.gov/pubmed/30513051
  • Marcus CL, Brooks LJ, Draper KA, Gozal D, Halbower AC, Jones J, et al. Diagnosis and management of childhood obstructive sleep apnea syndrome. Pediatrics 2012;130(3):576–84. https://www.ncbi.nlm.nih.gov/pubmed/22926173
  • Mitchell RB. Adenotonsillectomy for obstructive sleep apnea in children: outcome evaluated by pre- and postoperative polysomnography. Laryngoscope 2007;117(10):1844–54. https://www.ncbi.nlm.nih.gov/pubmed/17721406
  • Sanchez T, Castro-Rodriguez JA, Brockmann PE. Sleep-disordered breathing in children with asthma: a systematic review on the impact of treatment. J Asthma Allergy 2016;9:83–91. https://www.ncbi.nlm.nih.gov/pubmed/27143940
  • Tan HL, Kheirandish-Gozal L, Gozal D. Obstructive sleep apnea in children: update on the recognition, treatment and management of persistent disease. Expert Rev Respir Med 2016;10(4):431–9. https://www.ncbi.nlm.nih.gov/pubmed/26949836
  • Venekamp RP, Hearne BJ, Chandrasekharan D, Blackshaw H, Lim J, Schilder AG. Tonsillectomy or adenotonsillectomy versus non-surgical management for obstructive sleep-disordered breathing in children. Cochrane Database Syst Rev 2015;(10):CD011165. https://www.ncbi.nlm.nih.gov/pubmed/26465274