Low-dose aspirin for management of Kawasaki disease

For children with Kawasaki disease, low-dose aspirin is used for its antiplatelet effect, particularly when fever has resolved and if thrombocytosis is present; the usual dosage is:

aspirin 3 to 5 mg/kg orally, daily for at least 6 to 8 weeks. aspirin aspirin aspirin

Low-dose aspirin is continued until follow-up echocardiography has been performed, typically for 6 to 8 weeks after resolution of fever. Low-dose aspirin may be stopped if no coronary artery lesions are detected on echocardiography; however, if lesions are detected, continue low-dose aspirin indefinitely, and monitor the coronary arteries regularly with echocardiography.