Introduction to rheumatoid factor-negative polyarticular JIA

Onel, 2022Petty, 2004Ringold, 2019

Rheumatoid factor (RF)–negative polyarticular juvenile idiopathic arthritis (JIA) may affect both large and small joints, often in a symmetrical pattern.

Although asymptomatic anterior uveitis is less common in RF-negative polyarticular JIA than in oligoarticular JIA, regular slit-lamp screening examinations are still required (see JIA-associated uveitis for advice on screening interval and duration).