Contraindications and precautions for progestogen-only contraceptive pills

The only contraindication (UKMEC 4) to progestogen-only contraceptive pills (POPs) is current breast cancer.

POPs require expert clinical judgment or referral (UKMEC 3) in individuals with:

unexplained vaginal bleeding (suspicious for a serious condition) before investigation for the cause
past breast cancer
severe (decompensated) cirrhosis
hepatocellular adenoma or malignant liver tumour
ischaemic heart disease, stroke or transient ischaemic attack (TIA) that develops during use.

See the Faculty of Sexual and Reproductive Healthcare website for a full list of precautions to POPs.