Adverse effects of medical abortion

Mifepristone can cause short-term nausea, vomiting and anorexia. If vomiting occurs within 1 hour of administration, provide a repeat prescription for mifepristone and misoprostol, with an antiemetic administered beforehand.

Although misoprostol can cause nausea and vomiting (as well as transient fevers, chills and diarrhoea), vomiting does not significantly alter its effectiveness because it is absorbed buccally, provided the tablets do not fall out of the mouth during vomiting.