Key references: Delayed puberty in males

  • Klein DA, Emerick JE, Sylvester JE, Vogt KS. Disorders of puberty: an approach to diagnosis and management. Am Fam Physician 2017;96(9):590–9. https://www.ncbi.nlm.nih.gov/pubmed/29094880
  • Rohayem J, Hauffa BP, Zacharin M, Kliesch S, Zitzmann MGerman Adolescent Hypogonadotropic Hypogonadism Study Group. Testicular growth and spermatogenesis: new goals for pubertal hormone replacement in boys with hypogonadotropic hypogonadism? -a multicentre prospective study of hCG/rFSH treatment outcomes during adolescence. Clin Endocrinol (Oxf) 2017;86(1):75–87. https://www.ncbi.nlm.nih.gov/pubmed/27467188
  • Stancampiano MR, Lucas-Herald AK, Russo G, Rogol AD, Ahmed SF. Testosterone therapy in adolescent boys: the need for a structured approach. Horm Res Paediatr 2019;92(4):215–28. https://www.ncbi.nlm.nih.gov/pubmed/31851967
  • Zacharin M, Sabin MA, Nair VV, Dabadghao P. Addition of recombinant follicle-stimulating hormone to human chorionic gonadotropin treatment in adolescents and young adults with hypogonadotropic hypogonadism promotes normal testicular growth and may promote early spermatogenesis. Fertil Steril 2012;98(4):836–42. https://www.ncbi.nlm.nih.gov/pubmed/22763096