Chelation therapy

Chelating agents bind metals and allow them to be eliminated from the body; however, there is little evidence to support the use of chelation therapy for acute ingestions and its use is not common. Choice of chelating agent depends on the type of poisoning (eg arsenic, iron, lead) and whether the exposure is acute or chronic—see individual monographs.

The major practical barrier to the use of chelation therapy is difficulty in obtaining the chelating agents1. If considering chelation therapy, seek advice from a clinical toxicologist.

1 Most chelating agents are not registered for use in Australia but are available via the Special access scheme (SAS). Pharmacists or emergency staff should check the emergency and life-saving drugs register for their state. This register lists hospitals that hold specific SAS drugs that may be borrowed in an emergency.Return