Decontamination

For apixaban or rivaroxaban poisoning, offer gastrointestinal decontamination with activated charcoal to alert and cooperative patients who are able to protect their airway and present within 6 hours after the estimated ingestion timeWang 2014Ollier 2017. If the patient is intubated, activated charcoal can be given any time after ingestion via a nasogastric or orogastric tube—confirm correct placement of the nasogastric or orogastric tube beforehand.