Treatment of asymptomatic Chlamydia trachomatis infection

To treat asymptomatic chlamydial infection, useDukers-Muijrers, 2019Lau, 2021Peuchant, 2022Workowski, 2021:

1doxycycline 100 mg orally, 12-hourly for 7 days doxycycline doxycycline doxycycline

OR for pregnant patients or patients likely to be nonadherent to doxycycline

2azithromycin 1 g orally, as a single dose; for anorectal infection repeat the dose of azithromycin 1 g orally 12 to 24 hours later. azithromycin azithromycin azithromycin

Advise patients toOng, 2023:

  • abstain from sexual contact for 7 days after treatment starts, or until treatment is completed and symptoms have resolved (if treating a syndrome or symptomatic infection), whichever occurs later
  • notify partners from the last 6 months of the need to seek testing.

Perform a test of cure at least 4 weeks after treatment completion for patients who are pregnant, or those with an anorectal infection who were treated with azithromycinOng, 2023.