Treatment

For treatment of oesophageal candidiasis in adults with HIV infection, use:

1 fluconazole 200 mg orally, for the first dose, then 100 mg daily for 14 days. For dosage adjustment in adults with kidney impairment, see fluconazole dosage adjustment candidiasis, oesophageal (adult with HIV) fluconazole

2 itraconazole (Lozanoc capsule) 100 mg orally, daily for 14 days¹ candidiasis, oesophageal (adult with HIV) itraconazole itraconazole itraconazole

OR (if an oral liquid formulation is required)

2 itraconazole (Sporanox oral liquid) 200 mg orally, daily for 14 days¹. itraconazole itraconazole itraconazole

If response to therapy is inadequate, seek expert advice.

In patients with newly diagnosed HIV, exclude other infections before starting antiretroviral therapy for HIV infection. For patients with HIV and oesophageal candidiasis but no other infection, start antiretroviral therapy as soon as possible (see Initial antiretroviral therapy for HIV infection in adults).

¹ Oral preparations of itraconazole are not bioequivalent; appropriate dosing and administration depends on the preparation.Return