Practical information on using foscarnet

Foscarnet is active against herpesviruses (eg cytomegalovirus [CMV]). It is usually used intravenously. For immediately sight-threatening CMV retinitis, foscarnet may be used intravitreally in combination with systemic antiviral therapy.

The risk of nephrotoxicity with intravenous foscarnet is reduced by co-administration with fluid before and during treatment.