Continuation therapy for Streptococcus pyogenes (group A streptococcus) bloodstream infections

Australian Commission on Safety and Quality in Health Care (ACSQHC), 2023

For adults and children with Streptococcus pyogenes bloodstream infections, once they have clinically improved, switch to oral therapy. Use:

For oral continuation therapy for adults and children who report a hypersensitivity reaction to penicillin, seek expert advice.

A total treatment duration of 7 days (intravenous + oral) is often adequate for patients who are not immunocompromised and do not have a deep-seated or uncontrolled source of infectionBalance Investigators, 2024.