Management of adults reporting trimethoprim+sulfamethoxazole hypersensitivity

Managing a patient reporting hypersensitivity to trimethoprim+sulfamethoxazole depends on many factors. Consider whether trimethoprim+sulfamethoxazole therapy is necessary, and the balance of benefits and harms.

In selected patients with severe immediate or nonsevere (immediate or delayed) hypersensitivities (for definitions Common terminology used when discussing antimicrobial hypersensitivity), desensitisation may be appropriate. Seek expert advice.

For the management of children reporting hypersensitivity to trimethoprim+sulfamethoxazole, seek expert advice.