Vancomycin continuous infusion dosing in children not initially treated with an intermittent vancomycin infusion
For children not initially treated with intermittent vancomycin infusion, the continuous infusion should be immediately preceded by a loading dose; use:
vancomycin intravenously (loading dose)vancomycin
15 mg/kg (actual body weight) up to 1 g given over 1 hour as a single dose
FOLLOWED BY
vancomycin intravenously (initial continuous infusion dose)
60 mg/kg/day (actual body weight) up to 4 g, as continuous infusion.
Children on a vancomycin continuous infusion should have a random plasma concentration measured 24 hours after starting the infusion – see Vancomycin trough plasma concentration monitoring in young infants and children.