Prolactinomas during breastfeeding and postpartum

Women with a prolactinoma can safely breastfeed—no evidence suggests that suckling stimulates prolactinoma growth.

If possible, delay starting or resuming dopamine agonist therapy in a woman who wishes to breastfeed, as it suppresses lactation. If treatment cannot be delayed, and the woman is able to produce breastmilk, breastfeeding may be continued with caution—monitor the infant for adverse effects such as drowsiness, insomnia, dry mouth or constipation.

After pregnancy, the serum prolactin concentration can decrease or normalise; reduction in prolactinoma size can also occur. Reassess serum prolactin concentration 2 months after cessation of breastfeeding, or, if not breastfeeding, 2 months after delivery.