Proton pump inhibitors for patients taking antithrombotic therapy for acute coronary syndromes

Collet, 2021Visseren, 2021

Concurrent use of a proton pump inhibitor is recommended for patients taking dual antiplatelet therapy (DAPT) who are at high risk of gastrointestinal bleeding, and in patients taking triple antithrombotic therapy (DAPT plus an oral anticoagulant)Valgimigli, 2018. Use:

pantoprazole 40 mg orally, daily. pantoprazole pantoprazole pantoprazole

Omeprazole and esomeprazole should not be used with clopidogrel because they may reduce the pharmacodynamic response to clopidogrelCollet, 2021.