Antiplatelet therapy for NSTEACS

For patients with confirmed non–ST elevation acute coronary syndrome (NSTEACS), dual antiplatelet therapy is recommended. Start aspirin immediately; it will likely have been given at first medical contact (eg in the ambulance). A P2Y₁₂ inhibitor (clopidogrel, prasugrel, ticagrelor) with aspirin is usually given for all patients with confirmed NSTEACS. The timing and type of the P2Y₁₂ inhibitor should be determined in consultation with the cardiology team, with consideration of bleeding risk, time to invasive coronary angiography and coronary anatomy. See Overview of management of non-ST elevation acute coronary syndrome (NSTEACS) for an overview of management of NSTEACS.