Key references: Safety of drugs used for diabetes during pregnancy

  • Feig DS, Donovan LE, Zinman B, Sanchez JJ, Asztalos E, Ryan EA, et al. Metformin in women with type 2 diabetes in pregnancy (MiTy): a multicentre, international, randomised, placebo-controlled trial. Lancet Diabetes Endocrinol 2020;8(10):834-44. https://www.ncbi.nlm.nih.gov/pubmed/32946820
  • Given JE, Loane M, Garne E, Addor MC, Bakker M, Bertaut-Nativel B, et al. Metformin exposure in first trimester of pregnancy and risk of all or specific congenital anomalies: exploratory case-control study. BMJ 2018;361:k2477. https://www.ncbi.nlm.nih.gov/pubmed/29941493
  • Rowan JA, Hague WM, Gao W, Battin MR, Moore MP. Metformin versus insulin for the treatment of gestational diabetes. N Engl J Med 2008;358(19):2003-15. https://www.ncbi.nlm.nih.gov/pubmed/18463376
  • Society of Obstetric Medicine of Australia and New Zealand (SOMANZ). Guideline for the management of hypertensive disorders of pregnancy. SOMANZ; 2014. https://www.somanz.org/guidelines