Who to treat for hepatitis C

All patients with hepatitis C, defined by the presence of HCV RNA in blood using a polymerase chain reaction (PCR) assay, should be considered for treatment, except those with limited life expectancy (less than 12 months) due to comorbidities not related to hepatitis C or the liver. In patients with cirrhosis, treatment should be started as early as possible.

Certain patients should be referred to a specialist for treatment—see Which patients to refer for specialist management.