Drug regimens using ketamine or propofol for conscious sedation in adults

Note: Ketamine and propofol must only be administered by anaesthetists or other appropriately trained and credentialed medical practitioners.

If conscious sedation is appropriate for an adult, the following drug regimens may be used; see Principles of conscious sedation for a discussion of their use, including monitoring, equipment and physical facilities, and staffing requirements.

Ketamine must only be used for conscious sedation by anaesthetists or other appropriately trained and credentialed medical practitioners. For conscious sedation in adults, use:

ketamine 0.25 to 0.5 mg/kg intravenously, as a single dose. If necessary, give 0.25 mg/kg intravenously, every 2 to 3 minutes until adequate sedation and analgesia is achieved. Use the lower end of the dose range in older or frail patients. Use ideal body weight in overweight patients. Do not exceed a total dose of 1 mg/kg. procedural sedation and analgesia, conscious sedation (adults) ketamine    

Propofol must only be used for conscious sedation by anaesthetists or other appropriately trained and credentialed medical practitioners. For conscious sedation in adults, use:

propofol 0.25 to 0.5 mg/kg intravenously, as a single dose. If necessary, give 0.25 mg/kg intravenously, every 2 to 3 minutes until adequate sedation is achieved. Use the lower end of the dose range in older or frail patients. Use ideal body weight in overweight patients. Do not exceed a total dose of 1 mg/kg. procedural sedation and analgesia, conscious sedation (adults) propofol