Zolpidem or zopiclone use during pregnancy

Zolpidem or zopiclone use during pregnancy should be guided by the considerations outlined in Principles of psychotropic use during pregnancy.

Use zolpidem or zopiclone with caution in pregnancy; there are limited safety data. The antenatal use of either drug has been associated with small-for-gestational age and low birth weight neonates. Zolpidem may also increase the risk of preterm or caesarean delivery. Increased rates of congenital malformations have not been reported.

If the patient has been taking zolpidem or zopiclone long term to treat insomnia, see here for advice on stopping the drug.