Stem-cell transplantation for severe systemic sclerosis

Myeloablative autologous haematopoietic stem-cell transplantation is increasingly considered as a viable therapeutic option for patients with poor-prognosis systemic sclerosisSullivan, 2018. It may benefit patients with poor-prognosis systemic sclerosis who have single organ-system disease, such as interstitial lung disease or kidney disease, that has not yet resulted in organ failure.