Formulations of combined hormonal contraception

Formulations of combined hormonal contraception available in Australia are listed in Formulations of combined hormonal contraception available in Australia.
Table 1. Formulations of combined hormonal contraception available in Australia

Printable Table

Combined hormonal contraceptive formulations

monophasic vaginal ring

monophasic oral

triphasic oral

quadriphasic oral

Estrogen dose (micrograms)

estrogens estrogens estrogens

Progestogen dose (micrograms)

progestogens progestogens progestogens

Brand name examples [NB1]

monophasic vaginal ring

ethinylestradiol 2700 (15 micrograms/24 hours over 3 weeks)

etonogestrel 11 700 (120 micrograms/24 hours over 3 weeks)

NuvaRing

monophasic oral

estetrol 14 200

drospirenone 3000

Nextstellis [NB2]

estradiol 1500

nomegestrol 2500

Zoely [NB2]

ethinylestradiol 20

levonorgestrel 100

Femme-Tab ED 20/100 [NB3]

Lenest 20 ED

Loette

Microgynon 20 ED

Micronelle 20 ED

ethinylestradiol 20

drospirenone 3000

Yaz [NB2]

ethinylestradiol 30

desogestrel 150

Madeline

Marvelon

ethinylestradiol 30

dienogest 2000

Valette

ethinylestradiol 30

drospirenone 3000

Petibelle

Yasmin

ethinylestradiol 30

gestodene 75

Minulet

ethinylestradiol 30

levonorgestrel 150

Eleanor 150/30 ED [NB3]

Evelyn 150/30 ED [NB3]

Femme-Tab ED 30/150 [NB3]

Lenest 30 ED [NB3]

Levlen ED [NB3]

Microgynon 30 ED

Micronelle 30 ED [NB3]

Monofeme [NB3]

Nordette

Seasonique [NB4]

ethinylestradiol 35

cyproterone 2000 [NB5] [NB6]

Chelsea-35 ED

Diane-35 ED

Estelle-35 ED

Jene-35 ED

Juliet-35 ED

Laila-35 ED

ethinylestradiol 35

norethisterone 500

Norimin [NB3]

ethinylestradiol 35

norethisterone 1000

Norimin-1 [NB3]

ethinylestradiol 50 [NB7]

levonorgestrel 125

Microgynon 50 ED

mestranol 50 [NB7]

norethisterone 1000

Norinyl-1

triphasic oral formulation

phase 1 (6 pills): ethinylestradiol 30 + levonorgestrel 50

phase 2 (5 pills): ethinylestradiol 30 + levonorgestrel 75

phase 3 (10 pills): ethinylestradiol 40 + levonorgestrel 125

Logynon ED [NB3]

Trifeme [NB3]

Triquilar ED [NB3]

quadriphasic oral formulation

phase 1 (2 pills): estradiol valerate 3000 alone

phase 2 (5 pills): estradiol valerate 2000 + dienogest 2000

phase 3 (17 pills): estradiol valerate 2000 + dienogest 3000

phase 4 (2 pills): estradiol valerate 1000 alone

Qlaira [NB8]

Note:

PBS = Pharmaceutical Benefit Scheme; TGA = Therapeutic Goods Administration

NB1: List may not be complete.

NB2: Nextstellis, Yaz and Zoely are packaged with 24 active (hormone) pills and 4 inactive pills.

NB3: At the time of writing, these formulations are available on the PBS (all those containing norethisterone and some containing levonorgestrel). See the PBS website for current information.

NB4: Seasonique is packaged with 84 pills containing ethinylestradiol+levonorgestrel 30+150 micrograms, and 7 pills containing ethinylestradiol 10 micrograms.

NB5: Contraceptives containing cyproterone are only approved by the Australian TGA for use in individuals with hirsutism or severe acne.

NB6: Formulations containing cyproterone should not be used for Quick Start unless pregnancy can be reasonably excluded, because there is a theoretical risk of feminisation of a male fetus. For general advice about excluding pregnancy, see Starting intrauterine contraception.

NB7: Formulations containing high-dose estrogen (50 micrograms of ethinylestradiol or mestranol) pose an unacceptable risk of venous thromboembolism. They are not recommended for contraception or management of conditions such as hirsutism, endometriosis, polycystic ovary disease, premenstrual syndrome or premenstrual dysphoric disorder. Their role is limited to short-term use to manage acute severe uterine bleeding.

NB8: Qlaira is packaged with 26 active (hormone) pills and 2 inactive pills. It only provides immediate contraception if started on day 1 of the menstrual cycle. If started on day 2 or later, it takes 9 days to become effective.