Depot medroxyprogesterone

Depot medroxyprogesterone has not been studied for its effect on heavy menstrual bleeding, but it induces amenorrhoea after a year in 50 to 70% of individuals using it for contraception. It requires less user involvement than oral medications as it is injected every 12 weeks, and is an alternative treatment if the LNG-IUD and contraceptive vaginal ring are not suitable.

Use:

If bleeding has not settled after 6 months of treatment, specialist referral is required to investigate for underlying causes. Also consider indications for earlier referral.

For more information on depot medroxyprogesterone, including contraindications, advantages and disadvantages of use, see Depot medroxyprogesterone.