Neurotoxicity

Neuromuscular paralysis is a less common effect of snake envenoming than coagulopathy (fewer than 10% of cases). It presents as a progressive descending flaccid paralysis, characterised by:

  • early ptosis
  • extraocular muscle weakness (diplopia, blurred vision)
  • bulbar weakness (dysphagia)
  • progressive respiratory muscle paralysis
  • peripheral weakness.

Antivenom may prevent the development and progression of neurotoxicity, but rarely reverses it. Spontaneous recovery occurs over a period of days to weeks.